Views: 0 Author: Site Editor Publish Time: 2021-03-20 Origin: Site
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin.
A machine that enables the testing of blood samples for the blood clotting properties in the individual is a Coagulation Analyzer. Clotting of blood is one of the most important properties. When an individual is hurt, the clotting kicks in to stamp the blood flow by converting it into a gel. In the case of the excessive or insufficient amount of clotting, it can be extremely harmful. Therefore, a need for a coagulation analyzer was recognized to find relevant anomalies and enable quick treatment for the same.
Traditionally, coagulation tests were performed manually and were highly limited in terms of type of tests, accuracy and standardization of results, traceability of results, impact of manual errors etc. Over time, the systems have evolved from almost manual to the automated stage going with the need for higher accuracy, test menu, reproducibility and traceability. One of the best instruments for the testing is the semi-automated coagulation analyzer. Let’s see how it works.
How does Automated Coagulation Analyzers Work?
The most modern technology available for coagulation analyzers or coagulometers today is the photo-optical detection technology. Consequently, coagulometers or coagulation analyzers that work based on photo-optical detection principles should be the most ideal option for a lab to go for. In this technology, in contrast to a traditional analyzer that utilized magnetic bars with optics to detect clots, this analyzer uses a photo optic method that involves the detection of clots photometrically without the use of magnetic bars.
The coagulation test is performed to calculate factors which are the certain proteins in the blood responsible for the formation of a clot. A person having abnormal coagulation test results might be suffering from Thrombohillia (an excessive amount of clotting and high calculated factor), or Hemophilia (an excessive amount of bleeding and low calculated factor).